maybe you think saffron for depression is a Advertising proposition but this is not true. research and laboratory data shows that saffron benefits for treatment depression. clinical trials, laboratory data and experience say to us: yes, saffron is good for prevention and treatment depression.
Effect of saffron for depression
We have some of clinical trials that refer to the efficiency of saffron for improve and healing depression. All of this researches mention that saffron isn’t a complete drug for treatment of depression and saffron is Ancillary medicine for this target.
So, first read the conclusion of this researches and then notice the experimental tips that comes in the last of this article. sometimes we know the cause of problem and try to find a solution for it and sometimes we don’t know the cause and trust to our experience.
in this case and about saffron we have both of the solutions. Scientific findings and human experiences.
in a 6 weeks clinical trials, 40 person that evaluated as depressed were examined. they have at least rate 18 based on Hamilton Depression Rating Scale. in this research a group take (30 mg/day) saffron twice a day and the second group just take placebo.
result of this clinical trials shows that saffron threads (stigma) have a positive effect on depression rating scale and help to accelerate recovery and control side effects of antidepressants drugs.
another clinical trials conduct based on compare the efficiency of saffron versus the imipramine in the treatment of depression. in this trials a group of patient received saffron (30mg/day) and the second group received imipramine (100 mg/day) for 6 weeks.
the result of this case showed the saffron in this dose have equal or even higher efficiency with imipramine. but the main point comparing is the side effect of the chemical drugs and herbal drugs.
analyze of Pharmacological Action of Saffron
laboratory research shows that saffron have two critical antidepressant factor which are crocin and safranal. it’s not exactly clear the mechanism action of these factors but they guess maybe the crocin and safranal can be regulating mount of serotonin reuptake and NEP, dopamine rate.
these two factor are small part of saffron active ingredients. in other means maybe there’s other factors that are efficient for treatment of depression. the researches are going…
saffron and side effects of antidepressants
We know antidepressant drugs such as fluoxetine and other tricyclic drugs can be useful for depression but this is not all of the story. Maybe this be a rule, nothing can be perfect.
When we using drugs for treatment our disorders an extrinsic factor enter our body and do something in all over of our body. Not in specific section but in all over of body. If fluoxetine take to your brain you will be good but this not occur and it effect on some of other organs too.
Sexual disorders is one of this side effect that we can suffer it. Research shows that sexual dysfunction is one the most common symptom or side effects of depression. scientist trying to find some solution for this problem and one of the effective and safe way is herbal drug.
role of saffron in treatment Sexual dysfunction
let’s look at to some of research that be done in this case. The conclusion of this research is that:
It seems saffron may safely and effectively improve some of the fluoxetine-induced sexual problems including arousal, lubrication, and pain.
some of neurologists use combine treatment method that involve herbal drug such as saffron and common antidepressants drugs.
saffron for depression dosage
there’s not the exact amount of saffron for depression dosage but what is clear that using (30 mg/daily) for 4 weeks can be useful.
there’s lots of documents from traditional Iranian medicine that refer to saffron benefits for depression. formerly there’s not any drug or other method to treatment of depression and only way was herbal drugs. we don’t know if it was exactly effective or not but we know saffron can control Disease progress.
but saffron isn’t enough only. saffron can be efficient as adjuvant therapy and can reduce sides effect of disease. also some of saffron based drug is produced that are useful for depression treatment.