Maybe you think saffron for depression is an advertising statement, but this isn’t true. researches and laboratory data have proven saffron benefits for the treatment of depression. Clinical trials, laboratory data, and experience say to us: Yes, saffron is good for the prevention and treatment of depression.
What is depression and what can saffron do to prevent or improve depression?
The answer to the first question is clear and let’s talk about the second one. Saffron is a good choice for prevention, treat and reducing depression effects on our body and soul. This isn’t mean saffron can replace drugs or other treatment methods, this means is, saffron can be the best supplement for this disorder.
Effect of Saffron for Depression
We have some clinical trials that refer to the efficiency of saffron for improving and healing depression. All of this researches mention that saffron isn’t a complete drug for the treatment of depression and saffron can be an ancillary medicine for this target.
So, first, read the conclusion of this researches and then notice the experimental tips that come in the last of this article. Sometimes we know the cause of the problem and try to find a solution for it and sometimes we don’t know the cause and trust our experience.
In this case and about saffron we have both of the solutions. Scientific findings and human experiences.
Saffron for Depression Dosage
There isn’t any exact amount of saffron for depression dosage but what is clear is that using (30 mg/daily) for 6 weeks can be useful. So you can use saffron based on this dosage for 6 weeks and after this period you can use it with your food or drinks such as saffron tea or saffron milk. this way can help us to avoid depression.
1. Clinical Trials
In a 6 weeks clinical trial, 40 persons that evaluated as depressed were examined. They have at least rate 18 based on Hamilton Depression Rating Scale. In this research, a group of them take (30 mg/day) saffron twice a day, and the second group just takes a placebo.
placebo = It looks like medicine but has no active ingredients
The result of these clinical trials shows that saffron threads (stigma) have a positive effect on the depression rating scale and help to accelerate recovery and control the side effects of antidepressants drugs.
Other clinical trials were conducted based on comparing the efficiency of saffron versus imipramine in the treatment of depression. in this trial, a group of patients received saffron (30mg/day) and the second group received imipramine (100 mg/day) for 6 weeks.
The result of this case showed the saffron in this dose have equal or even higher efficiency with imipramine. But the main point comparing is the side effect of the chemical drugs and herbal drugs.
2. Analyze the Pharmacological Action of Saffron
Laboratory research shows that saffron has two critical antidepressant factors which are crocin and safranal. it isn’t exactly clear the mechanism action of these factors but they guess maybe the crocin and safranal can be regulating mount of Serotonin reuptake and NEP, Dopamine rate in our nervous system.
As you know serotonin is our happiness hormone and if we can regulate its rate, we can control depression. This mechanism is the basis of antidepressant drugs and most of them do this action.
Scientists are working and can do something for depression treatment. Some of the new methods are in the developing process and the future of depression treatment will be bright. But this isn’t enough, we must join these efforts and at least do something for preventing depression.
These two factors are a small part of saffron’s active ingredients. In other words, maybe there are other factors that are efficient for the treatment of depression. The researches are going…
3. Saffron and Side Effects of Antidepressants
We know antidepressant drugs such as Fluoxetine and other tricyclic drugs can be useful for depression but this isn’t the whole of the story. Maybe this is a rule, nothing can be perfect.
When we use drugs for the treatment of our disorders, an extrinsic factor enters our body and does something all over our body, not in a specific section but in all over of body. If Fluoxetine takes to your brain only, you will be good but this doesn’t occur commonly and it can effects some other organs too.
Sexual disorders are one of these side effects that we will suffer. Researches show that sexual dysfunction is one of the most common symptoms or side effects of depression. Scientists trying to find some solution for this problem and one of the effective and safe ways is herbal medicinal.
Role of Saffron in Treatment Sexual Dysfunction
Let’s look at some of the researches that have been done in this case. The conclusion of this research is as below:
It seems saffron may safely and effectively improve some of the fluoxetine-induced sexual problems including arousal, lubrication, and pain.
Some neurologists use combine treatment methods that involve herbal drugs such as saffron and common antidepressants drugs. This method can help us to survive depression and also stay away from depression’s side effects.
Some of the researches show that saffron can accelerate the treatment process and help us to back to our normal life. Also, scientists have proven that saffron can help to control disease progression and avoid major depression.
4. Experimental Observations
There are lots of documents from traditional medicine that refer to saffron benefits for depression. Formerly there isn’t any drugs or other methods for the treatment of depression and the only way was herbal drugs. We don’t know if it is exactly effective or not, but we know saffron can control disease progression and this is excellent.
But saffron isn’t enough only. Saffron can be efficient as adjuvant therapy and can reduce sides effect of the disease. also, some saffron-based drug is produced that is useful for depression treatment.